Rabu, 01 Desember 2021

Abbott Vitamin D Injection

Abbott Vitamin D Injection

Arachitol 600000IU 1ML injection
Uses and Benefits
Uses and Benefits

Arachitol 600000IU 1ML injection is a vitamin D preparation, primarily used to treat vitamin deficiency and its associated issues. Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of magnesium, calcium and phosphate, and many other biological effects. The injection uses these components to give relief from arthritic pain and stiffness. It is commonly prescribed for the treatment of joint pains, osteomalacia, osteoarthritis, rickets, hypophosphatemia, hypoparathyroidism (causing low blood calcium) and acts as building blocks for various tissues like bones, cartilage, tendons, teeth, etc. The injection improves overall joint health of individual. However, the uses of the injection mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor's discretion.

Composition
Composition

The active ingredient of Arachitol 600000IU 1ML injection is Cholecalciferol 600000 IU/ML

Mechanism of Action of Drugs
Mechanism of Action of Drugs

Arachitol 600000IU 1ML injection contains calcium supplement that regenerates and maintains mechanical properties of the cartilage and provide strength in load bearing bones, thereby improving flexibility in joints. Cholecalciferol, a fat-soluble sterol, helps your body absorb more calcium from your diet. It aids in regulation of calcium and phosphate homeostasis and bone mineralisation.

Contraindications and Cautions
Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using Arachitol 600000IU 1ML injection:

  • Hypersensitivity to any of the ingredients used in the injection
  • Sarcoidosis
  • Nephrolithiasis
  • Hypophosphatemia
  • Caution:
  • High levels of vitamin D (hypervitaminosis D)
  • Malabsorption
  • Phenylketonuria
  • Kidney stones
  • Renal impairment
  • Pregnancy and lactation
Side Effects
Side and Adverse Effects

Arachitol 600000IU 1ML injection is usually well tolerated when taken in the recommended dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:

  • Loss of appetite
  • Dry mouth
  • Muscle pain
  • Increased thirst
  • Metallic taste
  • Vomiting
  • Constipation
  • Stomach upset
  • Difficult urination

Rare but more serious adverse effects may include:

  • Swelling of face, lips
  • Pruritis, rash
  • Chest pain
  • Flatulence
  • Blue or grey skin colour
  • Kidney stones
How to Use
How to Use

Do not self-administer Arachitol 600000IU 1ML injection, your nurse or trained physician will give you the medicine. Follow all the instructions given by your doctor carefully. Continue to take the medicine till the time you see an improvement in your health conditions or as advised by your doctor. If a dose is missing, it should be taken as soon as possible.
This injection may be taken with or without food. It may be taken with food to reduce gastric discomfort.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun.

Overdosage

Avoid taking medicine more than the prescribed dosage. Since Accuzon 1GM injection will be given by doctor or nurse, therefore it is less likely that you will receive overdose of the medicine. Overdose can lead to hypercalcaemia; extreme hypercalcaemia may lead to coma and death. Irreversible renal damage and soft tissue calcification may occur as a result of prolonged hypercalcaemia in some patients. Depending on the dosage of Arachitol 600000IU 1ML injection, symptoms vary in individuals, you may experience one or more of the following symptoms:

  • Kidney stones
  • Muscle weakness
  • Fever
  • Blue or grey skin color
  • Bone pain
  • Cardiac arrhythmias (severe cases)
Warnings and Precautions
Warnings and Precautions

Use this injection on the advice of medical practitioner. Dose adjustments or complete avoidance of the Arachitol 600000IU 1ML injection may be required in the following conditions:

Kidney:

Caution is advised among people with kidney problems. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any renal problems, it is highly recommended that you consult doctor before the taking this injection.

Liver:

This medicine should be used with caution in patients with moderate to severe liver disease. If you have any hepatic problems, we recommend you to consult your doctor before the taking this injection.

Pregnancy:

Arachitol 600000IU 1ML injection should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

Lactation:

Use of excessive amounts of cholecalciferol in nursing mothers may result in hypercalcaemia in infants which may lead to supravalvular aortic syndrome, the features of which may include retinopathy, mental or growth retardation. We highly recommend that you consult your doctor before the taking this medicine.

Alcohol:

Consumption of alcohol with this medicine is not recommended as it increases side effects of the medicine. If you notice any unusual or abnormal reactions after taking the injection, report to your doctor immediately. If you consume alcohol on regular basis, relevant dose adjustments of the medicine may be necessary depending on your clinical condition.

Driving:

This injection does not cause drowsiness or dizziness. If you notice any abnormal reactions after taking the medicine, do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

Foods that are rich in oxalic acid (e.g., spinach) and phytic acid (e.g., whole cereals) may reduce calcium absorption by formation of insoluble calcium salts.

Drug Interactions:

Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Arachitol 600000IU 1ML injection with bile acid sequestrants such as cholestyramine/ colestipol, mineral oil, orlistat (as they can decrease the absorption), tetracyclines, benzalkonium chloride, antacids containing aluminium salts, thiazide diuretics (decreases urinary excretion of calcium), ibuprofen, diclofenac, indomethacin, meloxicam and other NSAIDs.

Precautions
  • Do not use this injection post the expiry date
  • Do not use this medication for durations longer than suggested by your doctor
  • Store at cool temperature (2-8 degree Celsius)
  • Do not freeze
FDA Pregnancy Category
FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Drug Composition information
What is cholecalciferol for:

This medication is an analogue of vitamin D, prescribed for hypocalcaemia, hypoparathyroidism, hypophosphataemia, renal osteodystrophy, and osteomalacia. Since it does not require any activation process by kidneys like other vitamin D supplements, more useful for people who have kidney problems.

How does cholecalciferol work:

It works by helping the body to use more of the calcium found in foods and supplements.

How should cholecalciferol be used:

It comes as a capsule to take by mouth, with food. It also comes as a solution for injection to be administered by a healthcare provider into the vein.

Common side effects of cholecalciferol :

Dry mouth, muscle pain, increased thirst, loss of appetite, vomiting, metallic taste, upset stomach, constipation, difficult urination.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking cholecalciferol :

Tell your doctor if you are allergic to any drugs. Some drugs like phenytoin, phenobarbital, prednisone and some laxatives may affect the availability. Inform your doctor if you have kidney or liver disease, pregnant, or planning to have surgery including dental procedures.

When do I need to seek medical help

Seek help if you have signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Inform doctor if you experience any bruising or bleeding, any rash, or if any side effect or health problem is not better or you are feeling worse.

Can I take cholecalciferol with other medicines:

This drug will only work if you get the right amount of calcium from your diet. If you are being treated with dialysis, your doctor may also prescribe a low phosphate diet. Follow these directions carefully. If you do not have kidney disease, you should drink plenty of fluids when taking this drug. If you have kidney disease, talk to your doctor about how much fluid you should drink each day.

Are there any food restrictions

Avoid alcohol and grapefruit juice.

How do I store cholecalciferol :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Vitamins

Frequently Asked Questions
Frequently Asked Questions
Q1. What is the use of the Arachitol 600000IU 1ML injection?

It is a vitamin D preparation, primarily used to treat vitamin deficiency and its associated issues. Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of magnesium, calcium and phosphate, and many other biological effects. The injection uses these components to give relief from arthritic pain and stiffness. It is commonly prescribed for the treatment of joint pains, osteomalacia, osteoarthritis, rickets, hypophosphatemia, hypoparathyroidism (causing low blood calcium) and acts as building blocks for various tissues like bones, cartilage, tendons, teeth, etc. The injection improves overall joint health of individual.

Q2. What are the side effects of the Arachitol 600000IU 1ML injection?

The injection is well tolerated when taken in prescribed dosage guidelines. Most common side effects include musculoskeletal pain (bone, muscle or joint pain), headache, back pain, flushing, itching, diarrhoea, constipation, gastrointestinal discomfort, dry mouth, vomiting, skin rashes and nausea. Its use may also lead to uncommon side effects such as anorexia, taste disturbances, difficult urination, cholestatic jaundice, hyperoxaluria, milk alkali syndrome.

Q3. Should we take Arachitol 600000IU 1ML injection with food or without food?

The injection can be taken with or without food. For better absorption, take the medicine with meals and avoid intake of large amounts of fibre-rich food.

Q4. What are the precautions to be followed while taking the Arachitol 600000IU 1ML injection?

If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised among patients with history of renal calculi, hypercalcaemia, hypophosphatemia, patients with suspected digoxin toxicity, iron metabolic disorders, ulcerative colitis, blood clotting disorders, renal impairment, patient with gall stones, hypo parathyroid disease, pregnancy and lactation.

Q5. Does Arachitol 600000IU 1ML injection make you sleepy?

The injection does not cause drowsiness or dizziness. If you notice any abnormal reactions after taking the injection, do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Q6. Is Arachitol 600000IU 1ML injection harmful? What does an overdose of Arachitol 600000IU 1ML injection lead to?

The injection is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to abdominal pain, kidney stones, muscle weakness, bone pain, mental disturbances, impaired biliary secretion and cardiac arrhythmias in severe cases.

Q7. Can I take Arachitol 600000IU 1ML injection during pregnancy?

The injection should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

Q8. Can Arachitol 600000IU 1ML injection be taken without a doctor's prescription?

Yes, you can take the medicine without doctor's prescription but if you notice any unusual or abnormal reactions after taking the injection, promptly seek medical attention.

Q9. Is it okay to drink alcohol while I am on the Arachitol 600000IU 1ML injection?

Interaction of alcohol with this medicine is unknown. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately. If you consume alcohol on regular basis, relevant dose adjustments of the medicine may be necessary depending on your clinical condition.

Q10. How to store Arachitol 600000IU 1ML injection?

Store the medicine at cool temperature (2-8 degree Celsius), do not freeze. Keep the injection according to the instructions mentioned on the pack or label.

Q12. Can we give Arachitol 600000IU 1ML injection to children?

The safety and efficacy of using this injection in children has not been clinically determined.

Q13. By when should I start seeing the results of the Arachitol 600000IU 1ML injection?

The duration required for this medicine to show its effect in the body is not clinically determined.

Q14. How long does the effect of Arachitol 600000IU 1ML injection last?

The duration for which this medicine remains active in the body is not clinically determined.

Q15. Can we take Arachitol 600000IU 1ML injection daily? If yes, how many injections can we take everyday?

Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration.

Q16. For how many days should I take the Arachitol 600000IU 1ML injection?

The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor's suggestion about how many days to take this medicine.

Q17. When should I take Arachitol 600000IU 1ML injection?

Use the medicine exactly as prescribed by your doctor for the dosage and duration.

Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

Abbott Vitamin D Injection

Source: https://www.medplusmart.com/product/ARACHITOL-600000IU-INJ/ARAC0002

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